Penicillin Production by High-yielding Strains of Penicillium chrysogenum1
نویسندگان
چکیده
منابع مشابه
Penicillin production by high-yielding strains of Penicillium chrysogenum.
The development and study of strains of Penicillium chrysogenum that give high yields of penicillin has been a major project at the University of Wisconsin during the past 12 years. Many thousands of cultures have been screened for their penicillin-producing ability in the Botany Department of the University. The methods used for the production and screening of mutants, the genealogy of the out...
متن کاملPenicillin Production by High-Yielding
The development and study of strains of Penicillium chrysogenum that give high yields of penicillin has been a major project at the University of Wisconsin during the past 12 years. Many thousands of cultures have been screened for their penicillin-producing ability in the Botany Department of the University. The methods used for the production and screening of mutants, the genealogy of the out...
متن کاملComparative Study of Penicillin Production with Vegetative and Spore Inoculum of Penicillium chrysogenum1
In commercial penicillin production the fermentation medium is usually seeded with a mycelial (vegetative) inoculum of Penicillium chrysogenum prepared by the following transfers: spores -+ germinator tank -seed tank. However, depending on the fermentation conditions, the operation in the germinator tank can be successfully eliminated. Goldschmidt and Koffler (1950) used spore-inoculated fermen...
متن کاملIncreased penicillin production in Penicillium chrysogenum production strains via balanced overexpression of isopenicillin N acyltransferase.
Intense classical strain improvement has yielded industrial Penicillium chrysogenum strains that produce high titers of penicillin. These strains contain multiple copies of the penicillin biosynthesis cluster encoding the three key enzymes: δ-(l-α-aminoadipyl)-L-cysteinyl-D-valine synthetase (ACVS), isopenicillin N synthase (IPNS), and isopenicillin N acyltransferase (IAT). The phenylacetic aci...
متن کاملPenicillin production by wild isolates of Penicillium chrysogenum in Pakistan
The present study was aimed at exploring the native wild isolates of Penicillium chrysogenum series in terms of their penicillin production potential. Apart from the standard medium, the efforts were made to utilize suitable agro-industrial wastes for the maximum yield of penicillin. Two series of P. chrysogenum were isolated from local sources and named as P. chrysogenum series UAF R1 and P. c...
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ژورنال
عنوان ژورنال: Applied Microbiology
سال: 1956
ISSN: 0003-6919
DOI: 10.1128/aem.4.5.277-283.1956